MiOXSYS test
The test is designed to determine the oxidation-reduction potential in the semen. A condition called oxidative stress is present if this potential is impaired.
The test is designed to determine the oxidation-reduction potential in the semen. A condition called oxidative stress is present if this potential is impaired.
What is the MiOXSYS test?
What is the MiOXSYS test?
The MiOXSYS test is designed to determine the oxidative-reductive potential in semen; a condition called oxidative stress is present if this potential is impaired.
It is caused by an imbalance between the amount of reactive oxygen species and other oxidants and the biological system’s ability to neutralise and remove them.
Excessive amounts of reactive oxygen species exert toxic effects on spermatozoa, leading, for example, to increased DNA fragmentation and protein oxidation. Environmental factors (lifestyle, stimulants, obesity), infections, as well as abnormalities of the genitourinary tract, such as cryptorchidism, varicocele or testicular torsion, all contribute to oxidative stress.
The test is performed using a special analyser and sensor, onto which a sample of specially prepared semen is deposited. By means of electrochemical technology, the analyser measures the oxidation-reduction potential in the semen.
About testing
Practised approaches
Electrochemical analysis

The test is performed using a special analyser and sensor, onto which a sample of specially prepared semen is deposited. By means of electrochemical technology, the analyser measures the oxidation-reduction potential in the semen.
Good to know
Preparation
for testing

We recommend the MiOXSYS test::
- To broaden the diagnosis of male infertility;
- To detect sperm abnormalities (reduced sperm morphology);
- To men over 35;
- To diagnose consecutive failed natural attempts and assisted reproduction procedures;
- In case of recurrent miscarriages;
- In case of infertility of unknown cause (idiopathic infertility);
- Prior to assisted reproduction procedures in order to select an appropriate sperm selection method and treatment method.
The following factors should be considered before proceeding with semen testing:
- Sexual abstinence
One of the key factors that affect the reliability of semen analysis is sexual abstinence, which should be from two to seven days. Both shorter and longer periods of sexual abstinence can affect parameters such as concentration, motility and sperm morphology. In the case of a repeated examination, the patient should maintain the same period of sexual abstinence.
- Stimulants and physical activity
Before semen testing, you should maintain a minimum of two days of alcohol abstinence and also limit excessive physical exertion for at least a day before the test.
No additional studies are required other than observing the standard semen preparation plan.
Sperm DNA fragmentation testing is only possible for sperm concentrations of >1 million/ml. The test may not be performed in cases of extreme oligozoospermia and azoospermia.
Semen testing should not be carried out during antibiotic therapy, in which case you should wait a minimum of 14 days after the end of the therapy. The result is also negatively affected by an elevated body temperature – in this case, it is recommended to perform the test 2.5 to 3 months after its onset.
Course of testing
FAQ
Frequently Asked Questions

We have two semen donation rooms in our clinic. These are located in a secluded part of the corridor, away from where other patients are waiting for their appointments. The room is equipped with a washbasin, a comfortable armchair and a TV with videos to help you donate sperm. The room is lockable from the inside and there is a tag on the door to advise whether the room is free or occupied. The room is communicated with the laboratory by an administration window that is locked from the inside; you leave your material for testing in this window.
In exceptional cases, the material can be delivered to the clinic from home in a container labelled with the patient’s full name and hour of material donation. You must then bring the sample in person to the laboratory no later than 30 minutes after ejaculation. During transport to the laboratory, the semen should not be subjected to shocks or temperature fluctuations (optimum transport temperature is 20-37°C). The transport temperature is most easily controlled by transporting the container in contact with the body, e.g. in a shirt or jacket pocket.
Yes, you can. Please remember that the material must not originate from a condom or intermittent intercourse.
Test price list
MiOXSYS – Oxidative stress assessment (ROS test) |
PLN 340 |
Semen testing package IV – full (extended computerised semen examination, DNA fragmentation, MAR IgG and IgA test, Mioxsys test – ROS test, HBA test) |
PLN 1 260 |