Genetic testing for women
There are many causes of infertility or problems with abnormal pregnancies at an early stage of gestation. Genetic abnormalities may be one of them. Our clinic provides a range of genetic tests to diagnose the cause of failures.
There are many causes of infertility or problems with abnormal pregnancies at an early stage of gestation. Genetic abnormalities may be one of them. Our clinic provides a range of genetic tests to diagnose the cause of failures.
What is genetic testing?
What is genetic testing?
The information embedded in DNA, which we inherit from our parents, is decisive for our lives, how we develop diseases, how susceptible we are to disease or, ultimately, our chances of having healthy offspring. Genetic testing entails analysing a person’s genetic material and detecting possible mutations.
The tests that are most commonly done to determine the cause of infertility or miscarriages are:
• CFTR gene mutation testing is a blood or saliva test. It allows for detecting mutations in the CFTR gene, responsible for the onset of cystic fibrosis and potentially causing infertility in men and women. The presence of an abnormal mutated gene may cause menstrual disorders and production of too thick cervical mucus.
• The KIR genotype test is a blood test designed for women. It consists of assessing the genotype (composition) of KIR receptors on uterine NK cells and may be helpful in the diagnosis of immune-mediated spontaneous abortions and some late complications during pregnancy.
• Karyotype testing is a blood test done in both men and women. Karyotype testing helps to determine the number and structure of chromosomes in the tested person.
• HLA-C typing is a blood test done in both men and women. This test can be helpful in diagnosing immuno-mediated infertility and frequent treatment failures.
• FMR1 gene premutation testing is a blood test done in women.This test is designed to detect a hereditary condition known as “fragile X chromosome syndrome,” which presents with a reduced ovarian reserve that is inadequate for age. The male offspring of women affected by this syndrome may present with intellectual disability, delayed psychomotor development, and behavioural disorders.
About testing
Practised approaches
Blood sample collection
Saliva sample collection
A sample containing DNA is required to perform a genetic test. Luckily, it is quick and painless, and only a small sample of saliva or blood is required for testing.
Good to know
Preparation
for testing
Genetic testing is done in cases of:
-
- infertility;
- recurrent miscarriage;
- failure of treatment with assisted reproductive technology, including treatment failure in an in vitro fertilisation program;
- poor semen parameters;
- birth of an older child with a genetic defect;
- primary amenorrhoea.
Blood tests do not require any special preparation. It is important that the patient stays adequately hydrated. The tests are done in the morning.
The patient must fast for saliva sample tests (AZF, CFTR). On the day of the examination, they must not smoke, chew gum nor brush their teeth. If there is a problem with bleeding gums, the test should be postponed until the condition has resolved.
Course of testing
Test price list
| Peripheral blood lymphocyte karyotype |
PLN 490 |
| CFTR gene testing – 36 mutations |
PLN 850 |
| CFTR gene testing – 7 mutations |
PLN 550 |
| Fragile X chromosome syndrome – analysis for presence of premutation and dynamic mutation consisting of a repeat expansion (CGG) in the 5’UTR of the FMR1 gene |
PLN 850 |
| Molecular KIR typing |
PLN 550 |
| Molecular HLA-C typing |
PLN 550 |
| Molecular KIR = HLA-C typing |
PLN 1 050 |
Opinions
How patients see us
I would like to wholeheartedly thank the ARTVIMED staff for making our dream of becoming parents come true. Our beloved baby son was born on 15 May this year.
Thanks to the physicians at the clinic, the whole IVF procedure was successful on the first try 🙂 We received the best care at each step. I had the opportunity to meet several doctors at the clinic during my appointments, and each one proved to be an outstanding professional.
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Opinion (Google) |
I highly recommend this doctor. Competent, committed, empathetic. Specific treatment plan. You know you are in good hands.
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Opinion by B. on Dr. Joanna Figuła (Znany Lekarz) |
Thanks to the Doctor, we welcomed our son into the world 2 weeks ago.
We found this doctor after several years of struggling to conceive a child and being treated by specialists who knew nothing about infertility. The doctor immediately outlined a definite plan of action, ordered the right diagnostic tests, and referred us to the hospital for testing. As a result, the treatment progressed in the right direction.[…]
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Opinion on Dr Ewa Posadzka Agnieszka L. (Znany Lekarz) |
The best doctor we could have come across; she managed our pregnancy with great commitment.
Patient and taking every moment to help or clear up doubts if necessary. Thanks to the Doctor, we are parents of a 5-month-old miracle baby. Highly recommended
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Opinion on Dr Agnieszka Wolak Anna (Znany Lekarz) |
Dr Baran is by far the gentlest, most thorough gynaecologist interested in the patient’s concerns that I have ever encountered.
Immense knowledge of endometriosis, the skills to provide complete ultrasound testing for it and the know how to guide a patient dealing with this unpleasant disease. […]
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Opinion on Dr. Rafał Baran (Znany Lekarz) |
I highly recommend pregnancy management. My past experience with other doctors was that there was little to be gained from the appointments, the doctors were reluctant to tell me what they saw, unwilling to answer questions, and Ms Joanna answered every single one, demonstrating an enormous amount of patience. Highly recommended.
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Opinion on Dr. Joanna Figuła Katarzyna (Znany Lekarz) |
Although our little sunshine is already 6 years old, so far, when I look at her, I still have Dr Chrostowski and the Artvimed clinic in my mind… Dr Chrostowski has got that something about him that, when you are in his office, you know that you couldn’t have found a better place. I will always highly recommend ARTVIMED to everyone.
Ps. I still am in awe of how the embryologists work…how they ‘managed’ to create such a miracle… 😉 Thank you for being there
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Opinion (Google) |
Very matter-of-fact doctor; she informs you thoroughly about everything and explains everything comprehensively. She informed me of the treatment plan and was very kind, gentle and understanding.
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Opinion on Dr Katarzyna Doroszewska (Znany Lekarz) |
We would like to thank the entire ARTVIMED Team – our little miracle was born 2 weeks ago. Many thanks are due, in particular, to Dr Posadzka, through whom the right diagnostic work began, and to Dr Chrostowski, who guided further treatment, punctures, and transfer. I also had the pleasure of dealing with most of the doctors during the course of my diagnosis and each one showed a great deal of support and professionalism. We would also like to thank the Embryology Team – without you, our son would not be here. Thank you for the beautiful work of the whole clinic!
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Opinion (Google) |
