Comprehensive endometrial assessment (EndomeTRIO)

EndomeTRIO is a test allowing for a comprehensive assessment of the endometrium.
EndomeTRIO is a test allowing for a comprehensive assessment of the endometrium.

What is a EnomeTRIO test?

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What is a EnomeTRIO test?

The assay allows for running a total of three tests with a single endometrial biopsy sample:

 

The ERA test (Endometrial Receptivity Analysis) helps to ascertain the most convenient time to perform the embryo transfer into the uterine cavity, boosting the chances of success of this procedure (it establishes when the so-called implantation window occurs in the cycle).

 

The EMMA test or Endometrial Microbiome Metagenomic Analysis helps to establish whether the microbiotic environment (the so-called microbiome) of the uterine cavity is suitable for embryo implantation.

 

The ALICE test (Analysis of Infectious Chronic Endometritis) detects bacteria causing chronic endometritis.
About testing

Practised approaches

ERA test

Endometrial biopsy

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The material to be assessed is obtained by endometrial biopsy.

Good to know

Preparation

for testing

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Testing is recommended if:

  • past attempts at in vitro fertilisation have been unsuccessful due to lack of embryo implantation;
  • there are recurrent spontaneous abortions, biochemical pregnancies;
  • Patient’s age is over 35 years;
  • Patient’s BMI is over 30;
  • Endometrial atrophy is present;
  • Patient has been diagnosed with adenomyosis.

In a natural cycle, the EndomeTRIO test is performed approximately seven days after the LH hormone is secreted.

If the patient is on hormonal stimulation, a sample of the endometrium (mucous membrane of the uterine cavity) is collected on the fifth day after ovarian puncture, or after five days of progesterone intake in an artificial (pharmacological) cycle.

You must report to the clinic on the date set by your attending physician.

Depending on the patient’s clinical situation, the physician orders specific hormonal blood tests.

  • Pregnancy
  • Acute inflammation (of the vagina, uterine cavity, appendages)
  • Genital tract bleeding or spotting

Course of testing

Stage 1

Preparation

The patient is asked to prepare for smear collection by removing her clothes from the waist down. For added comfort, she may choose to wear a disposable skirt. The patient lays down on the gynaecological chair.

Stage 2

Biopsy

Once the gynecological speculum is inserted, the physician takes a sample of the endometrium by guiding a thin catheter into the uterine cavity.

Stage 3

After testing

The test is short; during the test, the patient may feel slight discomfort, and after the test, there may be minor genital spotting and lower abdominal pain.

Stage 4

Shipment of material

The collected material is transferred to a special medium and stored at a low temperature and then sent to the IGENOMIX laboratory in Spain.

Stage 5

Test results

Test results are usually available within 20 days after testing.

Test price list

EndomeTRIO package (ERA + ALICE + EMMA test) (with endometrial biopsy)
PLN 5 300
EMMA / ALICE TEST (with endometrial biopsy)
PLN 3 600
ERA TEST (with endometrial biopsy)
PLN 4 200
Opinions

How patients see us

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I would like to wholeheartedly thank the ARTVIMED staff for making our dream of becoming parents come true. Our beloved baby son was born on 15 May this year.

Thanks to the physicians at the clinic, the whole IVF procedure was successful on the first try 🙂 We received the best care at each step. I had the opportunity to meet several doctors at the clinic during my appointments, and each one proved to be an outstanding professional.

Opinion (Google)
by Ewelina T.

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I highly recommend this doctor. Competent, committed, empathetic. Specific treatment plan. You know you are in good hands.

 

Opinion by B. on Dr. Joanna Figuła (Znany Lekarz)

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Thanks to the Doctor, we welcomed our son into the world 2 weeks ago.

We found this doctor after several years of struggling to conceive a child and being treated by specialists who knew nothing about infertility. The doctor immediately outlined a definite plan of action, ordered the right diagnostic tests, and referred us to the hospital for testing. As a result, the treatment progressed in the right direction.[…]

Opinion on Dr Ewa Posadzka Agnieszka L. (Znany Lekarz)
by Agnieszka L.

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The best doctor we could have come across; she managed our pregnancy with great commitment.

Patient and taking every moment to help or clear up doubts if necessary. Thanks to the Doctor, we are parents of a 5-month-old miracle baby. Highly recommended

Opinion on Dr Agnieszka Wolak Anna (Znany Lekarz)
by Anna

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Dr Baran is by far the gentlest, most thorough gynaecologist interested in the patient’s concerns that I have ever encountered.

Immense knowledge of endometriosis, the skills to provide complete ultrasound testing for it and the know how to guide a patient dealing with this unpleasant disease. […]

Opinion on Dr. Rafał Baran (Znany Lekarz)
by M.Ż.

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I highly recommend pregnancy management. My past experience with other doctors was that there was little to be gained from the appointments, the doctors were reluctant to tell me what they saw, unwilling to answer questions, and Ms Joanna answered every single one, demonstrating an enormous amount of patience. Highly recommended.

 

Opinion on Dr. Joanna Figuła Katarzyna (Znany Lekarz)
by Katarzyna

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Although our little sunshine is already 6 years old, so far, when I look at her, I still have Dr Chrostowski and the Artvimed clinic in my mind… Dr Chrostowski has got that something about him that, when you are in his office, you know that you couldn’t have found a better place. I will always highly recommend ARTVIMED to everyone.

Ps. I still am in awe of how the embryologists work…how they ‘managed’ to create such a miracle… 😉 Thank you for being there

Opinion (Google)
by Kasia S.

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Very matter-of-fact doctor; she informs you thoroughly about everything and explains everything comprehensively. She informed me of the treatment plan and was very kind, gentle and understanding.

Opinion on Dr Katarzyna Doroszewska (Znany Lekarz)
by Iwona G.

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We would like to thank the entire ARTVIMED Team – our little miracle was born 2 weeks ago. Many thanks are due, in particular, to Dr Posadzka, through whom the right diagnostic work began, and to Dr Chrostowski, who guided further treatment, punctures, and transfer. I also had the pleasure of dealing with most of the doctors during the course of my diagnosis and each one showed a great deal of support and professionalism. We would also like to thank the Embryology Team – without you, our son would not be here. Thank you for the beautiful work of the whole clinic!

Opinion (Google)
by Aga L.

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